Home contents
2017
   N# 1 | 2 | 3 |
2016
   N# 1 |
2015
   N# 1 | 2 | 3 | 4 | 5 |
2014
   N# 1 | 2 | 3 | 4 | 5 |
2013
   N# 1 | 2 | 3 | 4 | 5 |
2012
   N# 1 | 2 | 3 | 4 | 5 |
2011
   N# 1 | 2 | 3 | 4 | 5 |
2010
   N# 1 | 2 | 3 | 4 | 5 |
2009
   N# 1 | 2 | 3 | 4 | 5 |
2008
   N# 1 | 2 | 3 | 4 | 5 |
2007
   N# 1 | 2 | 3 | 4 | 5 |
2006
   N# 1 | 2 | 3 | 4 | 5 |
2005
   N# | 1 | 2 | 3 | 4 | 5 |
2004
   N# 1 | 2 | 3 | 4 | 5 |
2003
   N# 1 | 2 | 3 | 4 | 5 |
2002
   N# 1 | 2 | 3 | 4 | 5 |
2001
   N# 1 | 2 | 3 | 4 | 5 |
2000
   N# | 1 | 2 | 3 | 4 | 5 |
1999
   N# 1 | 2 | 3 | 4 | 5 |
1998
   N# 1 | 2 | 3 | 5 |
1997
   N# 1 | 2 | 3 | 4 | 5 |
1996
   N# 4 | 5 |

Click on the number of the review to see the content
Teaching bulletin CME
List of all teaching bulletins CME.
Editor reading committee
Editor reading committee.
To publish...
Instructions for authors
Archives Press and Books
Select of books and press articles.
Mailing list
News information letter.
Subscription prices


If you wish to adjust the size of the displayed characters, click in the high menu on "Your account" and choose the desired size.



  Contents > Previous page > Article detail print Order
o Issue N# 5 - 2005 o

PHONIATRICS

Vocal fold structure and vocal pathologies


Authors : C. Finck (Liège)

Ref. : Rev Laryngol Otol Rhinol. 2005;126,5:295-300.

Article published in french
Downloadable PDF document french



Summary : Our knowledge of vocal fold structure has profoundly evolved since the description by M.Hirano in 1974 of the laminar organization of the connective tissue of the human vocal fold, the lamina propria. The molecular composition of the extracellular matrix (ECM) of the lamina propria is essential in determining the viscoelastic properties of the tissue. This is particularly true in the superficial layer of the lamina propria (also called Reinke’s space). With the epithelium, Reinke’s space constitutes the vocal fold main vibrator. In normal subjects, the jelly like structure of the Reinke’s space is due to a very loose fibrous scaffolding and to a balance between the interstitial proteins of the ECM: Proteoglycans like decorin and hyaluronic acid and glycoproteins like fibronectin. Vibratory trauma leads, in disease states, to molecular modification of the extracellular matrix of Reinke’s space resulting in benign cordal lesions like nodules, submucosal fibrosis and vocal folds scars. Improving the knowledge of the homeostasis of Reinke’s space ECM can lead to improvement of the therapeutic and prevention strategies of vocal fold benign lesions. The main histologic and viscoelastic characteristics, as well as surgical treatment of cordal nodular lesions and scars are described. The recent researches in the field of regeneration of Reinke’s space are evoked.

Price : 10.50 €      order
|


Subscribe online - Pay by credit card!


© Copyright 1999-2018 - Revue de Laryngologie   Réalisation - Hébergement ELIDEE